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AESTHETIC DERMATOLOGY · PROCEDURESkin Renewal
Skin renewal procedures are approaches that support the skin's own repair and regeneration processes, rather than filling it from the outside or immobilizing it. They cover a wide range, from vitamin and hydration cocktails (mesotherapy) and plasma obtained from the person's own blood (PRP) to advanced regenerative procedures such as exosomes, stem cells, fibroblasts and SVF. Below you will find detailed information on what each procedure does, how it is performed, its results and duration, and what to consider.
Mesotherapy
Mesotherapy is based on delivering a cocktail prepared according to the skin's needs — made up of revitalizing components such as vitamins, minerals, amino acids, antioxidants and hyaluronic acid — into the upper layers of the skin with many small micro-injections. The aim is to hydrate, revitalize and improve the overall quality of the skin by nourishing it from within.
The content applied is determined according to the person's skin structure and needs; it is therefore a personalized approach, not "the same for everyone". It can be applied to the face, neck, décolleté and backs of the hands, and can also be performed as hair mesotherapy for the scalp. The best result is usually achieved with a program of sessions.
What is it used for?
- Dull, tired and dehydrated-looking skin
- Fine lines and loss of elasticity/radiance
- Supporting skin quality and vitality
- Support for nourishing hair follicles on the scalp (hair mesotherapy)
How is it performed?
It is applied by a specialist physician with a fine needle at many small points into the superficial layer of the skin. A numbing cream can be applied to the area for comfort. The procedure is brief and is usually planned as a program of several sessions.
Results and duration
The effect becomes apparent gradually as sessions progress, not all at once. Periodic maintenance is recommended to preserve the vitality gained.
Aftercare and precautions
After the procedure, short-lived mild redness or small needle marks may be seen; these usually subside quickly.
Who is it suitable for?
- Dull, tired-looking skin experiencing moisture loss
- Those experiencing the first signs of fine lines
- Those who want to maintain and support skin quality
How many sessions are needed and when is the effect seen?
A course of 3–6 sessions at intervals of a few weeks is usually planned; periodic repetition is then recommended to maintain the effect. The increase in hydration and vitality is mostly felt from the first sessions onward.
Daily life after the procedure
It is advised not to wear makeup on the day of the procedure and to avoid heavy exercise, sauna and swimming pools for the first 24 hours. The small bumps at the needle points mostly subside within a few hours; daily life continues without problems the next day.
Why does the choice of content matter?
There is no single standard mixture in mesotherapy. Since products containing hyaluronic acid, amino acids, vitamins, minerals or different active ingredients can be used, the treatment plan should be made according to the exact content of the product to be applied, not merely the name "mesotherapy". Evaluating the skin barrier, allergy history, medications used and the target area, and avoiding unnecessary multi-ingredient contents, provides a more controlled approach.
Mesotherapy during breastfeeding
There is generally no problem with performing it during breastfeeding. Before the procedure, the product used and the person's current health status are evaluated by the specialist physician.
How is the result monitored?
In the assessment after mesotherapy, not only radiance but also skin dryness, fine lines, elasticity and the daily care products the person uses are taken into account. It is not necessary to use the same cocktail in every session; the content can be changed according to the skin's response and seasonal needs. Rather than applying more frequently than necessary, intervals that allow the skin barrier to recover are planned.
Frequently asked questions
Is the procedure painful? Since very fine needles and, when needed, numbing cream are used, it is generally well tolerated.
In which season can it be done? It can be performed in any season; paying attention to sun protection is sufficient.
↑ Back to listPRP
PRP (Platelet-Rich Plasma) is a procedure that uses the person's own blood. A small blood sample is separated by a special process (centrifugation) to obtain the plasma portion rich in growth factors that support repair, and this plasma is returned to the skin or scalp. Growth factors can support skin repair, collagen production and overall vitality.
Because it is obtained from the person's own blood, it stands out as a natural approach with a low risk of allergy. It is preferred for skin revitalization in areas such as the face, neck and under the eyes, and for supporting hair follicles on the scalp. It is usually applied as a series of sessions.
What is it used for?
- Supporting skin quality, vitality and radiance
- Fine lines and refreshing the under-eye area
- Supporting hair follicles in hair loss (hair PRP)
- Natural support for the skin's repair processes
How is it performed?
First a small blood sample is taken, then the plasma is separated by centrifugation and applied to the skin with micro-injections or microneedling. The entire procedure is completed in the same session and is usually brief.
Results and duration
The effect is gradual and becomes apparent as sessions progress. Periodic maintenance may be recommended to sustain the results.
Aftercare and precautions
Mild redness, tenderness or small bruises may be seen after the procedure; they subside quickly.
Who is it suitable for?
- Those who want to support skin quality and vitality with a natural method
- Those who prefer an additive-free procedure derived from their own blood
- Those experiencing fine lines and reduced tissue quality
How many sessions are needed and when is the effect seen?
A course of 3–4 sessions a few weeks apart is usually applied; the effect gradually becomes apparent toward the end of the course. A repeat course once a year may be recommended.
Which procedures is it combined with?
PRP is often combined with Dermapen (microneedling) to increase penetration into the skin, and after golden needle or laser to support healing. The combination plan is determined by the physician according to the goal and the condition of the skin.
What does it mean that it is prepared from the person's own blood?
Since the plasma used in PRP is obtained from the person's own blood, no synthetic filler substance is introduced from outside. However, it is important that the procedure is prepared under sterile conditions and that the tubes used and the centrifugation protocol are appropriate. Platelet count, anemia, active infection, certain blood disorders and the use of blood thinners can affect the quality of the product obtained or the safety of the procedure.
PRP during breastfeeding
There is generally no problem with performing it during breastfeeding. Before the procedure, the product used and the person's current health status are evaluated by the specialist physician.
How is the response evaluated?
The effect of PRP develops over time by supporting tissue repair rather than creating immediate fullness. At follow-ups, skin quality — and in scalp treatments, the rate of shedding and the course of new hair growth — are evaluated. Since each person's platelet level and biological response differ, the same number of sessions may not suit everyone. If necessary, basic blood values and accompanying causes of hair loss are investigated separately.
Frequently asked questions
Is there a risk of allergy? Since it is prepared from the person's own blood, an allergic reaction is not expected.
Who is it not suitable for? It may not be suitable in certain blood disorders and with certain medications; suitability is evaluated at the examination.
↑ Back to listSalmon DNA
Salmon DNA treatments contain building blocks called polynucleotides , mostly derived from salmon. These building blocks are known for supporting skin repair and hydration. When delivered to the skin, they contribute to tissue repair, moisture balance and elasticity, helping the skin look healthier, fresher and more supple.
It is particularly preferred in thin and sensitive skin areas, under the eyes and for improving overall skin quality. Since it works by supporting the skin's own repair process, results appear over time and naturally; the best result is achieved with a program of sessions.
What is it used for?
- Supporting skin repair and moisture balance
- Loss of elasticity and fine lines
- Skin quality in the under-eye area
- Overall skin vitality and freshness
How is it performed?
It is applied by a specialist physician with micro-injections to the targeted area. The procedure is brief and is usually planned as a program of several sessions.
Results and duration
The effect is gradual; it becomes apparent as the skin repairs and hydrates. Periodic maintenance may be recommended to preserve the gains.
Aftercare and precautions
Short-lived mild redness or small marks may be seen after the procedure.
Who is it suitable for?
- Skin experiencing moisture loss and reduced elasticity
- Those with quality loss in thin, sensitive areas such as around the eyes
- Those who want to repair the skin barrier and achieve deep hydration
How many sessions are needed and when is the effect seen?
A course of 2–4 sessions is usually planned; improvement in hydration, radiance and elasticity is felt within a few sessions. It can be repeated as 1–2 courses per year.
Why does it stand out for the eye area?
Since the skin around the eyes is very thin, salmon DNA offers a gentle option that supports the repair and hydration of the area in cases where classic fillers are unsuitable or not desired. It is preferred for fine lines and a crepey appearance.
Product differences in polynucleotide treatments
Polynucleotide products referred to as salmon DNA are available in different formulations according to molecular density, concentration and target area. While more fluid products are preferred in thin-skinned areas such as around the eyes, different densities can be used in other areas of the face. Therefore, product selection should be based not only on the brand name but on the area to be treated and the skin structure.
Salmon DNA during breastfeeding
There is generally no problem with performing it during breastfeeding. Before the procedure, the product used and the person's current health status are evaluated by the specialist physician.
Follow-up and session plan
In polynucleotide treatments, the result is evaluated through skin hydration, elasticity, fine lines and especially tissue quality around the eyes. The small bumps seen after the first treatment are expected to disappear. The number of subsequent sessions may vary according to product concentration and skin needs. If other injection procedures will be performed in the same period, the skin's healing time should be taken into account.
Frequently asked questions
Is salmon DNA a filler? No; it does not add volume. Its purpose is to support the skin's repair, hydration and quality.
Can it be applied to people with fish allergy? Any allergy history must be reported to the physician; suitability is evaluated individually.
↑ Back to listYouth Vaccine
The youth vaccine is essentially an enriched mesotherapy approach. It is applied by delivering to the skin a balanced, standardized cocktail containing many components together, such as vitamins, minerals, amino acids, coenzymes, antioxidants and hyaluronic acid. The aim is to achieve a fresher, more rested look by nourishing and revitalizing the skin holistically, not from a single angle.
Due to the variety of components it contains, it is especially preferred for dull, tired skin with moisture loss. It can be applied to areas such as the face, neck, décolleté and backs of the hands, and the best result is usually obtained with a program of sessions.
What is it used for?
- Holistic skin revitalization and hydration
- Refreshing a dull, tired look and adding radiance
- Support in softening fine lines
- Improving overall skin quality
How is it performed?
Similar to mesotherapy, it is applied to the skin by a specialist physician with a fine needle at many small points. Numbing cream can be used for comfort; the procedure is brief.
Results and duration
The effect becomes apparent gradually as sessions progress; periodic maintenance is recommended to preserve the freshness gained.
Aftercare and precautions
Short-lived mild redness or small needle marks may be seen.
Who is it suitable for?
- Those experiencing early signs of aging (dullness, fine lines, loss of elasticity)
- Tired-looking skin with disrupted moisture balance
- Those who want natural support for glow and firmness
How many sessions are needed and when is the effect seen?
A protocol of 2–3 sessions a few weeks apart is usually applied; the effect settles gradually and is maintained with periodic repetition.
How does it differ from mesotherapy?
While in classic mesotherapy the content is blended for the individual, the youth vaccine is a ready-made, rich formula that offers many components together in balanced proportions. Which one to prefer is decided according to the skin's needs.
The "youth vaccine" is not a single product
Under the name youth vaccine, various products containing pure or lightly cross-linked hyaluronic acid, amino acids, peptides and different supporting components can be used. Therefore, the expected effect and safety assessment should be based on the actual content of the product to be used. The goal is to support the skin's moisture capacity, elasticity and a more vibrant look, rather than to add volume.
Youth vaccine during breastfeeding
There is generally no problem with performing it during breastfeeding. Before the procedure, the product used and the person's current health status are evaluated by the specialist physician.
How is the maintenance program created?
There is no single standard number of sessions for youth vaccine treatments. The skin's moisture loss, sun damage, age, smoking and daily care habits can affect the result. Periodic maintenance sessions can be planned to preserve the vitality and hydration support obtained after the first course. Sunscreen, gentle cleansing and appropriate moisturizer use do not replace the injection but help maintain the gains.
Frequently asked questions
At what age should one start? What matters is not chronological age but the skin's needs; the decision is made after evaluation.
How does it differ from filler? It does not add volume; it targets the skin's quality, hydration and elasticity.
↑ Back to listExosome
Exosomes are very small vesicles that play a role in intercellular communication; they carry growth factors and various signaling molecules. Acting like a kind of "messenger", they are thought to support communication between cells and the skin's repair processes. The aim of exosome treatments is to provide a more vibrant, fresh look by contributing to skin renewal and quality; they can also be used to support hair follicles on the scalp.
It is a relatively new and developing field. To increase its effectiveness, it is often performed together with procedures that facilitate penetration into the skin, such as microneedling or laser. Suitability and content should be evaluated individually and must be planned by a qualified physician.
What is it used for?
- Supporting skin renewal, quality and vitality
- Fine lines and a dull appearance
- Support for repair processes
- Supporting hair follicles on the scalp
How is it performed?
It is usually applied to the skin after microneedling or laser; in some cases it can also be done as micro-injections. It is usually planned as a program of sessions.
Results and duration
The effect is gradual and becomes apparent over time. Results may vary from person to person; periodic maintenance may be recommended.
Aftercare and precautions
Depending on the accompanying procedure, short-lived redness or tenderness may be seen. As it is an advanced/regenerative procedure, suitability and method must be determined by the physician.
Who is it suitable for?
- Those seeking regenerative support for skin quality
- Those who want to support healing after microneedling or laser
- People deemed suitable for hair and scalp support
How many sessions are needed and when is the effect seen?
3–4 sessions a few weeks apart are usually planned; it is often combined with procedures such as microneedling and the effect becomes apparent gradually.
Exosomes after laser and microneedling
When applied after laser or microneedling, exosomes are used to support the skin's recovery process; the aim is to help the redness period pass more comfortably and to support renewal.
Why is product standardization important?
In exosome treatments, the source of the product, its production method, sterility and content standardization are of great importance. Products on the market are not the same, and the content or clinical data of some products may be more limited than others. Therefore, expectations of results or safety should not be formed based on the name "exosome" alone; the regulatory status of the product used and the method of application should be evaluated by the physician.
Exosomes during breastfeeding
There is generally no problem with performing it during breastfeeding. Before the procedure, the product used and the person's current health status are evaluated by the specialist physician.
What is monitored during follow-up?
Since exosomes are usually used together with a procedure such as laser or microneedling, which procedure the redness and tenderness during the healing process stem from is evaluated together. Expected results vary according to the product and method used. At follow-up, healing of the skin barrier, color irregularity and tissue quality are monitored; a guaranteed rejuvenation result should not be expected from a single treatment.
Frequently asked questions
Is it applied on its own? It is mostly planned together with microneedling or device treatments to increase penetration.
Is the effect permanent? Since skin aging is an ongoing process, periodic maintenance is recommended.
↑ Back to listStem Cell
Stem cell-based treatments are part of regenerative aesthetics. Stem cells are cells with the potential to support tissue repair and regeneration. In aesthetic use, the goal is to contribute to a healthier, fresher and younger appearance by supporting the skin's repair and regeneration processes.
This is an advanced and developing field; the method applied, the content and the legal framework may differ by country and situation. Therefore, there is no "single method suitable for everyone"; suitability, approach and expectations must be evaluated by a qualified physician, under appropriate conditions and within a realistic framework.
What is it used for?
- Supporting the skin's repair and regeneration processes
- Contribution to skin quality and vitality
- The goal of an overall fresher appearance
How is it performed?
The method of application varies according to the chosen approach and is planned by a specialist physician under appropriate conditions. The process is individual.
Results and duration
The effect is gradual and results may vary from person to person. Realistic expectations and physician guidance are important.
Important note
Stem cell treatments are an advanced/regenerative field. Suitability, method and content must be evaluated by a qualified physician under appropriate conditions; exaggerated promises should be avoided.
Who is it suitable for?
- Those seeking advanced skin renewal
- Those experiencing a significant decline in tissue quality
- People found suitable for regenerative approaches
How does the process proceed?
The treatment plan is individual and is determined after a comprehensive evaluation. The effect emerges gradually through the tissue's self-repair processes; it requires patient follow-up.
Its place in regenerative aesthetics
Stem cell approaches fall under the heading of "regenerative aesthetics" together with PRP, exosomes and SVF. What these approaches have in common is that they support the tissue's own repair capacity rather than shaping it from the outside.
Managing expectations in regenerative treatments
Under the heading of stem cells, there may be different cellular sources, laboratory processes and application protocols. Therefore, which cell is used, how it is obtained and for what purpose it is applied should be clearly defined. Statements that offer guarantees such as "rejuvenation in a single session" do not reflect scientific reality. In the regenerative approach, results may be gradual and vary according to the person's age, tissue quality and the method of application.
Stem cell treatment during breastfeeding
There is generally no problem with performing it during breastfeeding. Before the procedure, the product used and the person's current health status are evaluated by the specialist physician.
Why can the follow-up process be long?
In cellular therapies, the biological response may develop gradually, and expecting dramatic change in a short time is not realistic. At follow-ups, tissue quality, the healing process and reactions in the treatment area are evaluated. The standards and level of evidence of the method used should be discussed openly, and results should be monitored with photographs and clinical examination. If an additional procedure is needed, the tissue is first allowed to heal completely.
Frequently asked questions
Can it be applied to everyone? No; suitability is evaluated in detail together with general health status and expectations.
When is the result seen? Since repair processes are spread over time, results become gradually apparent over weeks to months.
↑ Back to listFibroblast
Fibroblasts are the main cells responsible for producing collagen and elastin in the skin; in a sense, they are the "master builders" that provide the skin's firmness and elasticity. As the activity of these cells decreases with age, the skin loses its elasticity. Fibroblast-based treatments aim to support the skin's own capacity to produce collagen, thereby contributing to firmness, repair and a younger appearance.
This is a regenerative approach and the method applied may vary by person; suitability must be evaluated by a qualified physician. ("Fibroblast" here refers to a regenerative approach targeting skin cells; it is different from the device-based "plasma pen / plasma fibroblast" procedure.)
What is it used for?
- Supporting the skin's capacity to produce collagen
- Contribution to firmness and elasticity
- Supporting skin quality and repair
How is it performed?
The method of application varies according to the chosen approach and is planned by a specialist physician under appropriate conditions.
Results and duration
The effect is gradual; it becomes apparent as the skin's structural support strengthens. Results may vary from person to person.
Aftercare and precautions
As it is an advanced/regenerative procedure, suitability, method and expectations must be evaluated by a qualified physician.
Who is it suitable for?
- Those who want long-term skin renewal with their own cells
- Those experiencing significant loss of skin quality and elasticity
- People who can follow a staged, planned protocol
How does the process proceed?
Fibroblast cells from a small tissue sample taken from the person are multiplied in a laboratory environment and applied to the skin in spaced sessions. The process is therefore staged and requires planning; the effect develops gradually over months.
Why are fibroblast cells important?
Fibroblasts are the cells that produce collagen, elastin and hyaluronic acid. As their number and activity decrease with age, the skin begins to thin and loosen; the goal of this treatment is precisely to support this productive capacity.
Laboratory process and quality control
In fibroblast treatment, cells from a small skin sample taken from the person are multiplied in a laboratory and then reapplied. Therefore, not only the injection stage but also sampling, cell culture, sterility and quality control processes are important parts of the treatment. Transparent information should be obtained about the competence of the laboratory used and the traceability of the cellular product.
Fibroblast treatment during breastfeeding
There is generally no problem with performing it during breastfeeding. Before the procedure, the product used and the person's current health status are evaluated by the specialist physician.
How are results monitored?
Since the effect of fibroblast treatment is related to the cells settling into the tissue and collagen production processes, it is evaluated gradually. At follow-ups, fine lines, elasticity and skin texture are monitored. The storage and application protocol of the cellular product prepared from the same person must comply with laboratory standards. It should not be assumed that a single session will provide the same result for everyone; the follow-up plan should be created individually.
Frequently asked questions
Is it the same as the device-based "plasma fibroblast"? No; here the person's own cells are multiplied and applied. The plasma pen (Plexr) is a completely different, device-based procedure.
When is the effect seen? Since collagen and tissue renewal are spread over time, results become apparent over months.
↑ Back to listSVF Application
SVF (Stromal Vascular Fraction) is a mixture rich in regenerative cells obtained from the person's own adipose tissue. It is obtained by separating a small amount of fat tissue taken from a specific area of the body through a special process, and is used in regenerative aesthetics to support tissue repair and regeneration.
Being obtained from the person's own tissue makes this treatment a natural approach. However, as it is an advanced regenerative procedure, suitability, method and treatment conditions must be evaluated by a qualified physician, in an appropriate setting and with realistic expectations.
What is it used for?
- Supporting tissue repair and regeneration
- Contribution to skin quality and vitality
- General support within regenerative aesthetics
How is it performed?
First, a sample is taken from the person's own fat tissue with a minor procedure, then SVF is obtained through a special process and applied to the targeted area. The entire process is carried out by a specialist physician under appropriate conditions.
Results and duration
The effect is gradual and results may vary from person to person. Realistic expectations and physician guidance are important.
Important note
SVF is an advanced/regenerative procedure. Suitability, method and treatment conditions must be evaluated by a qualified physician in an appropriate setting.
Who is it suitable for?
- Suitable candidates seeking regenerative support
- Those experiencing significant loss of skin and tissue quality
- People found suitable after a comprehensive evaluation
How does the process proceed?
SVF (stromal vascular fraction) is obtained from the person's own fat tissue through a special process and applied to the target area. It is usually planned as a single procedure; when needed, it is supported with complementary treatments.
How does it differ from fat transfer?
In classic fat transfer, the aim is to add volume; in SVF, fat tissue is used only as a source, and the resulting cellular mixture is applied to support tissue repair and quality rather than volume.
Why is the SVF procedure not a simple injection?
SVF treatment uses the stromal vascular fraction obtained from fat tissue, and the process includes the stages of fat harvesting, processing and reapplication. Therefore, the procedure can be more invasive than classic mesotherapy or PRP. Sterile conditions, the separation method used, the quality of the cellular content and the medical setting where the treatment is performed are important for safety. Expected results vary from person to person, and a standard "rejuvenation" result cannot be guaranteed.
SVF treatment during breastfeeding
There is generally no problem with performing it during breastfeeding. Before the procedure, the product used and the person's current health status are evaluated by the specialist physician.
Healing and follow-up
In the SVF procedure, in addition to the injection area, the healing of the fat-harvest site is also monitored. Bruising, tenderness and edema may vary according to the extent of the procedure. At follow-ups, signs of infection, tissue healing and changes in the targeted area are evaluated. It should be clearly explained before the procedure that results may be gradual and that it is not always possible to give a standard duration for regenerative procedures.
Frequently asked questions
Where is it obtained from? It is prepared from the person's own fat tissue, under appropriate conditions and within the same session.
When is the result seen? Since tissue repair progresses gradually, the effect emerges over weeks to months.
↑ Back to listLet's Determine the Right Renewal Program for Your Skin Together
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